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  • 1.
    Abdelnur, Sofia
    Sophiahemmet University College.
    Omhändertagande av patienter med panikångest: en forskningsöversikt2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 2.
    Albertsson, Catharina
    et al.
    Sophiahemmet University College.
    Bolin, Louise
    Sophiahemmet University College.
    Hierarkins inverkan på omvårdnadsarbetet2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 3.
    Almqvist, Anneli
    Sophiahemmet University College.
    Faktorer som påverkar livskvalitet hos personer med kronisk obstruktiv lungsjukdom2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 4.
    Andersson, Jenny
    et al.
    Sophiahemmet University College.
    Hed, Michelle
    Sophiahemmet University College.
    Att begränsa spridning av infektioner orsakade av MRSA: en studie ur ett omvårdnads- och vårdpedagogiskt perspektiv2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 5.
    Andreassen, Sissel
    Sophiahemmet University.
    Life Situation, Information Needs, and Information Seeking in Patients with Oesophageal Cancer and their Family Members2006Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    This thesis explores the experiences of living with oesophageal cancer from the perspective of patients and family members. Also, their needs for information and how they seek information in relation to the illness were investigated. The thesis comprises one qualitative meta-analysis and three empirical studies including data from patients, family members, and health-care professionals.

     

    Paper I was a qualitative meta-analysis the aim of which was to extend knowledge about patients' and family members' experiences of living with oesophageal cancer and clinically similar cancer forms, mainly head and neck cancer. As a result of the thematic analysis we have shown that both patients and family members 'run into an unpredictable enemy'. Patients had to 'endure a fading body' Running into an unpredictable enemy and enduring a fading body led to -entering social silence' for patients and family members.

    The aim of paper II was to describe patients' experiences of living with oesophageal cancer and how they seek information in relation to the illness. Data was collected by qualitative interviews with thirteen patients and analysed by qualitative content analysis. The findings describe patients' experiences of receiving the diagnosis, their experiences of vague symptoms, and of existential concerns evoked by the illness. Undergoing investigations and treatment caused extreme tiredness. Patients experienced that the illness intruded upon their daily life. In order to manage the life-threatening illness- they sought information about the illness.

    The aim of paper III was to describe family members' experiences of living with a patient suffering from oesophageal cancer, their information needs and information seeking Data was collected by means of qualitative interviews with nine family members and analysed by qualitative content analysis. The findings describe that family members lacked awareness of the disease. When faced with the diagnosis, shock, stress, and disbelief were evoked . The cancer illness became intrusive into their everyday lives, routines, and life plans. Uncertainty about the course and prognosis of the disease was the main source of distress among them. In order to learn, obtain understanding for the illness, and manage this uncertainty, family members entrusted themselves to the experts and sought information from them.

    Paper IV was a pilot study the aim of which was to describe patients' and family members' information needs following a diagnosis of oesophageal cancer, their satisfaction with information obtained, and health-care professionals' perceptions concerning patients' and family members' information needs. Data was collected by means of a study-specific questionnaire and analysed with descriptive statistics. The results indicate that patients' and family members need for information following a diagnosis of oesophageal cancer was substantial and had not been adequately met by health-care professionals.

    In conclusion, the receipt of the diagnosis of oesophageal cancer was an abrupt change from feeling healthy with vague symptoms to having a life-threatening illness. The illness disrupts patients' and family members' social world and relationships, and the whole family is affected. For understanding and managing the illness, they sought information from health-care professionals, social networks, and various media

  • 6.
    Andreassen, Sissel
    et al.
    Sophiahemmet University.
    Randers, Ingrid
    Sophiahemmet University.
    Näslund, Erik
    Stockeld, Dag
    Mattiasson, Anne-Cathrine
    Sophiahemmet University.
    Patients' experiences of living with oesophageal cancer2006In: Journal of Clinical Nursing, ISSN 0962-1067, E-ISSN 1365-2702, Vol. 15, no 6, 685-95 p.Article in journal (Refereed)
    Abstract [en]

    AIMS: The aim of this study is to describe patients' experiences of living with oesophageal cancer and how they seek information. BACKGROUND: Oesophageal cancer is a devastating disease with poor prognosis. Nursing care for individuals with oesophageal cancer requires increased knowledge of how they experience illness and how it affects them. METHOD: Data were collected by semi-structured, qualitative interviews with 13 participants. Content analysis was used to analyse data. RESULTS: Four themes were identified: (i) Experiences of becoming a patient diagnosed with oesophageal cancer is distinguished by the participants' experiences of vague symptoms, of receiving the diagnosis and of existential concerns evoked by the illness. (ii) Experiences of undergoing investigations and treatment consist of the participants' experiences of extreme tiredness in relation to investigations and treatment. (iii) Experiences of intrusions in daily life is conceptualized by the participants' experiences of how the illness influenced their daily life. (iv) Managing a life-threatening illness consists of a variety of strategies, which the participants employed to manage their life-threatening illness. CONCLUSIONS: The participants were unprepared of receiving a diagnosis of oesophageal cancer. Dysphagia, fatigue and uncertainty influenced the participants' everyday life. To manage the illness one of their strategies was seeking for information. The physicians were considered the main source of information, but family as well as friends with medical knowledge were also acknowledged as valuable sources. RELEVANCE TO CLINICAL PRACTICE: Understanding patients' experiences of living with oesophageal cancer is important to improve nursing care. When caring for these patients, focus ought to be on the whole family. In nursing care, it is important to be aware of the effects of dysphagia and fatigue. Health-care professionals ought to organize meetings with fellow patients and recommend literature and websites that provide patients with high quality information.

  • 7.
    Axelsson, Lena
    et al.
    Sophiahemmet University.
    Björvell, Catrin
    Mattiasson, Anne-Cathrine
    Sophiahemmet University.
    Randers, Ingrid
    Sophiahemmet University.
    Swedish Registered Nurses' incentives to use nursing diagnoses in clinical practice2006In: Journal of Clinical Nursing, ISSN 0962-1067, E-ISSN 1365-2702, Vol. 15, no 8, 936-45 p.Article in journal (Refereed)
    Abstract [en]

    AIMS AND OBJECTIVES: The purpose of this study was to describe Registered Nurses' incentives to use nursing diagnoses in clinical practice. BACKGROUND: The use of nursing diagnoses is scarce in Swedish patient records. However, there are hospital wards were all nurses formulate and use nursing diagnoses in their daily work. This leads to the question of what motivates these nurses who do use nursing diagnoses in clinical practice. DESIGN: A qualitative descriptive design. METHODS: A purposeful sampling of 12 Registered Nurses was used. Qualitative interviews to collect data and a content analysis were performed. RESULTS: Five categories were identified: identification of the patient as an individual and as a whole, a working tool for facilitating nursing care, increasing awareness within nursing, support from the management and influence on the professional role. The principle findings of this study were: (i) that the Registered Nurses perceived that nursing diagnoses clarified the patient's individual needs and thereby enabled them to decide on more specific nursing interventions, (ii) that nursing diagnoses were found to facilitate communication between colleagues concerning patient care and thus promoted continuity of care and saved time and (iii) that nursing diagnoses were perceived to increase the Registered Nurses' reflective thinking leading to a continuous development of professional knowledge. CONCLUSIONS: The present findings suggest that the incentives to use nursing diagnoses originate from effects generated from performing a deeper analysis of the patient's nursing needs. Further research is needed to test and validate the usability and consequences of using nursing diagnoses in clinical practice. Motivating factors found in this study may be valuable to Registered Nurses for the use and development of nursing diagnoses in clinical care. Moreover, these factors may be of relevance in other countries that are in a similar situation as Sweden concerning application of nursing diagnoses.

  • 8.
    Bard, Sanna
    et al.
    Sophiahemmet University College.
    Bohgard, Stina
    Sophiahemmet University College.
    Sjuksköterskors omvårdnad av patienter med anorexia nervosa2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 9.
    Björklund, Hanna
    et al.
    Sophiahemmet University College.
    Falkman, Sofie
    Sophiahemmet University College.
    Omvårdnad av kvinnor som genomgår medicinsk abort2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 10.
    Björling, Gunilla
    et al.
    Sophiahemmet University.
    Johansson, Unn-Britt
    Sophiahemmet University.
    Andersson, G
    Schedin, Ulla
    Markström, A
    Frostell, C
    A retrospective survey of outpatients with long-term tracheostomy2006In: Acta Anaesthesiologica Scandinavica, ISSN 0001-5172, E-ISSN 1399-6576, Vol. 50, no 4, 399-406 p.Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: The Respiratory Unit (RU) at Danderyd University Hospital opened in 1982, with the expressed goal of supporting outpatients with long-term tracheostomy. The primary aim of this retrospective study in tracheostomized patients was to compare the need for hospital care in the 2-year period before and after the tracheostomy. METHODS: Data were collected from patient medical records at the RU, from the National Board of Health and Welfare, Sweden and from the Official Statistics of Sweden. The subjects were RU patients in 1982 (Group 1, n = 27) and in 1997 (Group 2, n = 106) with long-term tracheostomy surviving at least 4 years after the tracheostomy. RESULTS: Both groups had few and unchanged needs for hospital care after tracheostomy. They spent > or = 96% of their time out of hospital. In 1997, (group 2) the number of patients, diagnoses and need for home mechanical ventilation had increased. Life expectancy was assessed for patients in Group 1. Data showed that they lived as long as an age-matched and gender-adjusted control cohort. CONCLUSIONS: Long-term tracheostomy may not increase the need for hospital care and does not reduce life expectancy. These clinical observations were made in a setting where patients had regular access to a dedicated outpatient unit.

  • 11.
    Bolandpaz, Zahra
    et al.
    Sophiahemmet University College.
    Carter, Kim
    Sophiahemmet University College.
    Livskvalitet hos vuxna med astma2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 12. Brannan, J D
    et al.
    Gulliksson, Magdalena
    Anderson, S D
    Chew, N
    Seale, J P
    Kumlin, Maria
    Sophiahemmet University.
    Inhibition of mast cell PGD2 release protects against mannitol-induced airway narrowing2006In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 27, no 5, 944-50 p.Article in journal (Refereed)
    Abstract [en]

    Mannitol inhalation increases urinary excretion of 9alpha,11beta-prostaglandin F2 (a metabolite of prostaglandin D2 and marker of mast cell activation) and leukotriene E4. The present study tested the hypothesis that beta2-adrenoreceptor agonists and disodium cromoglycate (SCG) protect against mannitol-induced bronchoconstriction by inhibition of mast cell mediator release. Fourteen asthmatic subjects inhaled mannitol (mean dose 252+/-213 mg) in order to induce a fall in forced expiratory volume in one second (FEV1) of > or = 25%. The same dose was given 15 min after inhalation of formoterol fumarate (24 microg), SCG (40 mg) or placebo. Pre- and post-challenge urine samples were analysed by enzyme immunoassay for 9alpha,11beta-prostaglandin F2 and leukotriene E4. The maximum fall in FEV1 of 32+/-10% on placebo was reduced by 95% following formoterol and 63% following SCG. Following placebo, there was an increase in median urinary 9alpha,11beta-prostaglandin F2 concentration from 61 to 92 ng.mmol creatinine(-1), but no significant increase in 9alpha,11beta-prostaglandin F2 concentration in the presence of either formoterol (69 versus 67 ng.mmol creatinine(-1)) or SCG (66 versus 60 ng.mmol creatinine(-1)). The increase in urinary leukotriene E4 following placebo (from 19 to 31 ng.mmol creatinine(-1)) was unaffected by the drugs. These results support the hypothesis that the drug effect on airway response to mannitol is due to inhibition of mast cell prostaglandin D2 release.

  • 13.
    Brännlund, Henrik
    et al.
    Sophiahemmet University College.
    Lundholm, Joel
    Sophiahemmet University College.
    Preventivt arbete med övervikt och fetma bland barn i mellanstadiet2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 14.
    Carlson- Östlund, Emma
    et al.
    Sophiahemmet University College.
    Fägersten, Therese
    Sophiahemmet University College.
    Yrkesrelaterad stress inom vården av personer med demenssjukdom2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 15.
    Carmström, Jessica
    et al.
    Sophiahemmet University College.
    Sundell, Nina
    Sophiahemmet University College.
    Förutsättningar för en god nattsömn hos inneliggande patienter2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 16.
    Casemyr, Maria
    Sophiahemmet University College.
    NADA-akupunktur vid behandling av narkotikamissbruk: sjuksköterskors erfarenheter av NADA-akupunktur som en behandlingsmetod vid opiatabstinens2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 17.
    Cewers, Ingrid
    et al.
    Sophiahemmet University College.
    Skullman, Christina
    Sophiahemmet University College.
    Sjuksköterskans kunskap och patientens upplevelse vid postoperativ smärtbehandling2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 18.
    Ek, Lena
    et al.
    Sophiahemmet University College.
    Westring, Katarina
    Sophiahemmet University College.
    Taktil massage som beröringsmetod i omvårdnaden2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 19.
    El Hanach, Abdelelah
    Sophiahemmet University College.
    Livskvalitet hos äldre födda utomlands: att åldras i en annan kultur2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 20.
    Elfstrand, Emeli
    et al.
    Sophiahemmet University College.
    Söderström, Sofia
    Sophiahemmet University College.
    Metoder för viktminskning hos överviktiga barn2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 21.
    Engström Linse, Christina
    et al.
    Sophiahemmet University College.
    Pettersson, Maria
    Sophiahemmet University College.
    Kvinnors copingstrategier efter operation vid bröstcancer2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 22.
    Esbjörnsson, Linda
    et al.
    Sophiahemmet University College.
    Fluur, Louise
    Sophiahemmet University College.
    Kommunikationens betydelse i omvårdnaden av medvetslös patient2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 23.
    Evensen, Renate
    et al.
    Sophiahemmet University College.
    Östlund, Jenny
    Sophiahemmet University College.
    Vårdprogram för smärtbehandling och dess betydelse för omvårdnadsarbetet2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 24.
    Flodén, Tomas
    Sophiahemmet University College.
    Empowermentbaserad undervisning för patienter med diabetes2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 25. Gaber, Flora
    et al.
    Acevedo, F
    Delin, I
    Sundblad, Britt-Marie
    Palmberg, Lena
    Larsson, Kjell
    Kumlin, Maria
    Sophiahemmet University.
    Dahlén, Sven-Eric
    Saliva is one likely source of leukotriene B4 in exhaled breath condensate2006In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 28, no 6, 1229-35 p.Article in journal (Refereed)
    Abstract [en]

    Leukotriene (LT)B4 in exhaled breath condensate (EBC) has been reported to be elevated in airway inflammation. The origin of leukotrienes in EBC is, however, not established. The aims of this study are to measure LTB4 levels in EBC collected in two challenges characterised by a strong neutrophilic airway inflammation and to compare LTB4 levels in EBC with levels in sputum and saliva. LTB4 and alpha-amylase were measured in EBC from 34 healthy subjects exposed in a pig confinement building or to a lipopolysaccharide provocation. These markers were also measured in induced sputum in 11 of the subjects. For comparison, LTB4 and alpha-amylase were measured in saliva from healthy subjects. Only four out of 102 EBC samples had detectable LTB4 (28-100 pg x mL(-1)). alpha-amylase activity was detected in the LTB4-positive samples. In contrast, LTB4 was detected in all examined sputum supernatants in the same study (median 1,190 pg x mL(-1)). The median LTB4 level in saliva was 469 pg x mL(-1). High levels of leukotriene B4 in saliva and the presence of leukotriene B4 in exhaled breath condensate only when alpha-amylase was detected, indicate that leukotriene B4 found in exhaled breath condensate is the result of saliva contamination. As leukotriene B4 was consistently present in sputum supernatants, exhaled breath condensate may be inappropriate for monitoring airway leukotriene B4.

  • 26.
    Georgsson Öhman, Susanne
    et al.
    Sophiahemmet University.
    Saltvedt, Sissel
    Waldenström, Ulla
    Grunewald, Charlotta
    Olin-Lauritzen, Sonja
    Pregnant women's responses to information about an increased risk of carrying a baby with Down syndrome2006In: Birth, ISSN 0730-7659, E-ISSN 1523-536X, Vol. 33, no 1, 64-73 p.Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: Fetal screening for Down syndrome by an ultrasound examination, including measurement of fetal nuchal translucency, at 12 to14 weeks' gestation is presently being evaluated in a Swedish randomized controlled trial. Women at high risk were offered an amniocentesis to obtain a definite diagnosis. The aim of this study was to explore women's reactions and responses to information about being at high risk after the scan, with a special focus on reactions to a false positive test. METHOD: Interviews were conducted with 24 women within 1 week after the scan, in midpregnancy, and 2 months after the birth. The interviews were analyzed qualitatively. Down syndrome was confirmed in 4 women, who chose to terminate the pregnancy. The remaining 20 women had a false positive test. RESULTS: For the majority, the risk information caused strong reactions of anxiety and worries about the future. A typical way for women to cope was to "withhold" the pregnancy, to take a "timeout," and try to live as if they were not pregnant any longer. Some weeks later, when the women received normal results from the chromosome analysis, they resumed being pregnant. Six women ages more than 35 years who had a risk score lower than their age-related risk did not express similarly strong reactions. Two months after the birth of a healthy baby, most stated they would undergo the same procedure in a subsequent pregnancy. One woman still suffered from the experience when interviewed at 2 months after the birth, and another said she regretted participating in the fetal screening program. CONCLUSIONS: A false positive test of fetal screening for Down syndrome by ultrasound examination may cause strong reactions of anxiety and even rejection of the pregnancy. The prevalence of such reactions and possible long-term effects need further investigation.

  • 27. Gulliksson, Magdalena
    et al.
    Palmberg, Lena
    Nilsson, G
    Ahlstedt, S
    Kumlin, Maria
    Sophiahemmet University.
    Release of prostaglandin D2 and leukotriene C4 in response to hyperosmolar stimulation of mast cells2006In: Allergy. European Journal of Allergy and Clinical Immunology, ISSN 0105-4538, E-ISSN 1398-9995, Vol. 61, no 12, 1473-9 p.Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: Mannitol-induced bronchoconstriction in subjects with exercise-induced asthma is associated with increased urinary excretion of 9alpha, 11beta-PGF(2), a metabolite of prostaglandin D(2) (PGD(2)) serving as a mast cell marker. It has however been questioned whether or not human mast cells release PGD(2) and leukotriene C(4) (LTC(4)) after osmotic challenge with mannitol in vitro. METHODS: Cord blood-derived human mast cells were stimulated osmotically, immunologically or with a combination of both. Supernatants were analysed for PGD(2), LTC(4) and histamine contents with enzyme immunoassays. RESULTS: Significant release of de novo synthesized eicosanoids, predominantly PGD(2) [12 (8.8, 14) pmol/10(6)cells; median (25th, 75th percentile) but also LTC(4) (0.1 (0.08, 0.15) pmol/10(6) cells] were found in mast cells in vitro in response to 0.7 M mannitol stimulation. A massive release of histamine [70 (5.3)% of total; mean (SEM)] was also found. There were no correlations between the levels of released mediators after mannitol stimulation. In contrast, there was a correlation between release of PGD(2) and LTC(4), following immunological stimulation. CONCLUSION: The findings support that hyperosmolar challenge activates mast cells, but different than antigen stimulation.

  • 28. Gyllfors, Pär
    et al.
    Dahlén, Sven-Erik
    Kumlin, Maria
    Sophiahemmet University.
    Larsson, Kjell
    Dahlén, Barbro
    Bronchial responsiveness to leukotriene D4 is resistant to inhaled fluticasone propionate2006In: Journal of Allergy and Clinical Immunology, ISSN 0091-6749, E-ISSN 1097-6825, Vol. 118, no 1, 78-83 p.Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: Inhaled corticosteroids are highly effective in asthma, reducing inflammatory markers and bronchial hyperresponsiveness. Cysteinyl-leukotrienes are major mediators of airway obstruction and display proinflammatory effects. Although the synthesis of leukotrienes is not affected by corticosteroid treatment, the influence of corticosteroids on the leukotriene pathway remains unresolved. OBJECTIVE: We investigated whether or not bronchial responsiveness to leukotriene (LT) D(4) is reduced by fluticasone propionate in subjects with asthma. METHODS: In 13 subjects with mild asthma, inhalation challenges with methacholine and LTD(4) were performed on consecutive days before and after 2 weeks of treatment with inhaled fluticasone 500 mug, twice daily, in a double-blind, randomized, placebo-controlled study with crossover design and 3 weeks of washout between periods. Exhaled nitric oxide was measured as a marker of corticosteroid responsiveness, and baseline urinary LTE(4) concentrations as an index of cysteinyl-leukotriene biosynthesis. RESULTS: Fluticasone produced a significant decrease in methacholine responsiveness, corresponding to 2.6-fold shift in the PD(20) FEV(1), and a significant reduction in the levels of exhaled nitric oxide. By contrast, bronchial responsiveness to LTD(4) in the same subjects was unaffected by fluticasone, as were urinary LTE(4) concentrations. CONCLUSION: These new data indicate that neither the biosynthesis nor the actions of leukotrienes appear to be sensitive to inhaled corticosteroids. CLINICAL IMPLICATIONS: The study provides mechanistic support for the additive therapeutic efficacy of antileukotrienes and inhaled corticosteroids in asthma.

  • 29.
    Hallquist, Angela
    et al.
    Sophiahemmet University College.
    Winblad von Walter, Cecilia
    Sophiahemmet University College.
    Pedagogiska strategier för att vägleda personer med typ-II diabetes mot empowerment2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 30.
    Hammar, Sara
    et al.
    Sophiahemmet University College.
    Netterström, Johan
    Sophiahemmet University College.
    Sjuksköterskors hälsopedagogiska arbete med inriktning på övervikt hos tonåringar: en forskningsöversikt ur ett folkhälsoperspektiv2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 31.
    Herzog, Ann-Therese
    Sophiahemmet University College.
    Möjligheter att påverka livskvalitet hos patienter med schizofreni: en forskningsöversikt2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 32.
    Holmberg, Emma
    et al.
    Sophiahemmet University College.
    Nilsson, Linn
    Sophiahemmet University College.
    Kvinnors upplevelser av en abort2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 33.
    Härgestam, AnnaClara
    et al.
    Sophiahemmet University College.
    Sköldeberg, Elin
    Sophiahemmet University College.
    Primärpreventivt arbete mot HIV/AIDS: en studie utifrån intervjuer med sjuksköterskor och annan vårdpersonal vid ett sjukhus i Tanzania2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 34. Ihre, E
    et al.
    Gyllfors, Per
    Gustafsson, L E
    Kumlin, Maria
    Sophiahemmet University.
    Dahlén, B
    Early rise in exhaled nitric oxide and mast cell activation in repeated low-dose allergen challenge2006In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 27, no 6, 1152-9 p.Article in journal (Refereed)
    Abstract [en]

    Repeated low-dose allergen inhalation challenge mimics natural allergen exposure, providing a model for early mechanisms in the triggering of asthma. The current authors performed a controlled study to evaluate the time course of changes in exhaled nitric oxide fraction (F(e,NO)) and urinary biomarkers of airway inflammation. Eight subjects with mild allergic asthma completed two 7-day repeated low-dose challenge periods, with diluent and allergen, respectively. Subjects were symptom free at inclusion and were investigated when not exposed to specific allergen. Pulmonary function and symptoms were followed, and F(e,NO) and urinary mediators were correlated to changes in airway responsiveness to histamine and adenosine. Despite no change in pulmonary function (forced expiratory volume in one second mean+/-sem fall 0.3+/-0.7 versus 0.6+/-1.0%, for diluent and allergen, respectively) and no asthma symptoms, repeated allergen exposure, in contrast to diluent, caused significant increases in histamine responsiveness (2.3 doubling doses), an early and gradual increase in F(e,NO) (up to a doubling from baseline) and a small increase in the mast cell marker 9alpha11beta-prostaglandin F(2) after adenosine challenge. In conclusion, serial measurements of exhaled nitric oxide fraction have the potential to provide a very sensitive strategy for early detection of emerging airway inflammation and subsequent changes in airway hyperresponsiveness to histamine.

  • 35.
    Jernberg, Hans
    et al.
    Sophiahemmet University College.
    Jörgensen, Anna
    Sophiahemmet University College.
    Passiv eutanasi: en litteraturstudie av sjuksköterskors attityder och roll2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 36.
    Johansson, Unn-Britt
    Sophiahemmet University.
    Gastrointestinala komplikationer2006In: Omvårdnad vid diabetes / [ed] Karin Wikblad, Lund: Studentlitteratur , 2006, 233-41 p.Chapter in book (Other academic)
  • 37.
    Johansson, Unn-Britt
    et al.
    Sophiahemmet University.
    Wredling, Regina
    Sophiahemmet University.
    Diabetes hos vuxna2006In: Omvårdnad vid diabetes / [ed] Karin Wikblad, Lund: Studentlitteratur , 2006, 115-35 p.Chapter in book (Other academic)
  • 38.
    Johansson, Unn-Britt
    et al.
    Sophiahemmet University.
    Wredling, Regina
    Sophiahemmet University.
    Mätning av patientens välbefinnande och behandlingstillfredsställelse2006In: Omvårdnad vid diabetes / [ed] Karin Wikblad, Lund: Studentlitteratur , 2006, 343-47 p.Chapter in book (Other academic)
  • 39. Larsson, Britt-Marie
    et al.
    Kumlin, Maria
    Sophiahemmet University.
    Sundblad, Britt-Marie
    Larsson, Kjell
    Dahlén, Sven-Erik
    Palmberg, Lena
    Effects of 5-lipoxygenase inhibitor zileuton on airway responses to inhaled swine house dust in healthy subjects2006In: Respiratory Medicine, ISSN 0954-6111, E-ISSN 1532-3064, Vol. 100, no 2, 226-37 p.Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: Inhalation of swine house dust induces acute airway inflammation and increased bronchial responsiveness in healthy subjects. OBJECTIVE: The aim of the study was to investigate whether 5-lipoxygenase products such as leukotrienes may have a role in this reaction. METHODS: Twenty-three healthy subjects were randomised into two groups receiving treatment with either zileuton (600 mg) or placebo four times a day. After 5 days of treatment, all subjects were exposed for 3h in a swine barn. Bronchial responsiveness, exhaled nitric oxide (NO), and mediators in nasal lavage (NAL), blood and urine were measured before and after the exposure. RESULTS: The exposure induced an increased bronchial responsiveness to methacholine in both groups with 2-3 doubling concentration steps, no significant difference between treatments. Leukotriene E(4) in urine increased significantly following exposure in the placebo group from 37.3 (29.1-45.6) (mean (95% confidence interval)) ng/mmol creatinine to 47.7 (36.3-59.0) ng/mmol creatinine (P<0.05), but not in the zileuton group. The post-exposure increase of LTB(4) levels in NAL fluid was totally abolished in the zileuton group (P<0.05 vs. the placebo). The levels of exhaled NO increased significantly (P<0.01), two-fold in both groups. The PGD(2) metabolite 9alpha, 11beta-PGF(2) increased in placebo-treated subjects (P<0.01; P<0.05 vs. zileuton), strengthening mast cell participation. Neutrophil counts and levels of IL-6 in peripheral blood increased in both groups, with a significantly larger increase in zileuton treated subjects (P<0.05 and P<0.001, respectively compared to placebo). CONCLUSIONS: Pre-treatment with clinically recommended doses of the 5-lipoxygenase inhibitor zileuton did not affect the increase of bronchial reactivity induced by swine dust exposure. The intervention totally abolished the LTB(4) release in NAL fluid, but only partially inhibited the formation of leukotrienes as monitored by urinary levels. The enhanced increase of neutrophils and IL-6 in peripheral blood in the zileuton group, suggests that inhibition of 5-lipoxygenase may have pro-inflammatory effects.

  • 40.
    Lindberg, Ninni
    et al.
    Sophiahemmet University College.
    Lundell Rudberg, Susanne
    Sophiahemmet University College.
    Behov hos föräldrar till barn med cancer2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 41.
    Lindqvist, David
    et al.
    Sophiahemmet University College.
    Öhlin, Arvid
    Sophiahemmet University College.
    Tillämpning av god handhygien inom hälso- och sjukvård2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 42.
    Lindqvist, Emelie
    et al.
    Sophiahemmet University College.
    Hjerpe, Sandra
    Sophiahemmet University College.
    Sjuksköterskors attityder och kunskaper till donation från avlidna: en forskningsöversikt2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 43.
    Lockne, Kristina
    et al.
    Sophiahemmet University College.
    Odberger Kelly, Susanne
    Sophiahemmet University College.
    Samtal i möte med patienter i behov av palliativ omvårdnad: en kvalitativ intervjustudie med åtta sjuksköterskor2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 44.
    Löfgren, Elena
    Sophiahemmet University College.
    Bemötande av patienter med ångest2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 45.
    Maluenda, Talia
    Sophiahemmet University College.
    NADA-akupunktur som en komplementär behandling för patienter med opiatabstinens2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 46.
    Mannervik, Elisabeth
    et al.
    Sophiahemmet University College.
    Mesch, Malin
    Sophiahemmet University College.
    Sjuksköterskans information till patient som ska genomgå bröstrekonstruktion i samband med mastektomi och patientens uppfattning om information2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 47.
    Mörnberg, Jenny
    et al.
    Sophiahemmet University College.
    Neumüller, Anna-Lena
    Sophiahemmet University College.
    Beteende och fysiska skador hos barn som utsatts för incestuösa övergrepp: sjuksköterskans ansvar i vårdkedjan2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 48.
    Nilsson, Liv-Bente
    et al.
    Sophiahemmet University College.
    Stegarås, Charlotte
    Sophiahemmet University College.
    Sjuksköterskors upplevelser som mottagare och givare av taktil massage: en kvalitativ intervjustudie2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 49.
    Nordarp, Anneli
    et al.
    Sophiahemmet University College.
    Willner, Jeanette
    Sophiahemmet University College.
    Passiv eutanasi: ett etiskt dilemma2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 50.
    Nyambura Karngård, Daina
    Sophiahemmet University College.
    "Put life into their days!": the impacts of palliative care on life quality of HIV/AIDS patients in Kenya2006Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
12 1 - 50 of 59
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