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  • 1.
    Andersson, Helene
    et al.
    Sophiahemmet Högskola.
    Andreassen Gleissman, Sissel
    Sophiahemmet Högskola.
    Lindholm, Christina
    Sophiahemmet Högskola.
    Fossum, Bjöörn
    Sophiahemmet Högskola.
    Experiences of nursing staff caring for patients with methicillin-resistant Staphylococcus aureus.2016Inngår i: International Nursing Review, ISSN 0020-8132, E-ISSN 1466-7657, Vol. 63, nr 2, s. 233-241Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    BACKGROUND: Methicillin-resistant Staphylococcus aureus is a resistant variant of S. aureus and can cause pneumonia, septicaemia and, in some cases, death. Caring for patients with antibiotic resistant bacteria is a challenge for healthcare personnel. There is a risk of spreading the bacteria among patients and of healthcare personnel being infected themselves.

    AIM: To describe nursing staffs' experiences of caring for patients with methicillin-resistant S. aureus in Sweden.

    METHOD: A descriptive qualitative approach was used and 15 nurses from different hospitals and care units, including emergency and geriatric wards and nursing homes in Stockholm, were interviewed. All nurses had been involved in the care of patients with methicillin-resistant S. aureus, but not on a regular basis. The interviews were analysed using qualitative content analysis.

    FINDINGS: Three themes emerged from the data: feeling ignorant, afraid and insecure, feeling competent and secure and feeling stressed and overworked. The more knowledge the nurses acquired about methicillin-resistant S. aureus, the more positive was their attitude to caring for these patients.

    DISCUSSION AND CONCLUSION: Caring for patients with methicillin-resistant S. aureus without adequate knowledge of how to protect oneself and other patients against transmission may provoke anxiety among personnel. Guidelines, memos and adequate information at the right time are of central importance. Healthcare personnel must feel safe in their role as caregivers. All patients have the right to have the same quality of care regardless of the diagnosis and a lack of knowledge influences the level of care given.

    IMPLICATIONS FOR NURSING AND HEALTH POLICY: This study demonstrates the importance of education when caring for patients with infectious diseases. Hopefully, knowledge gained from our study can provide guidance for future health care when new diseases and infections occur.

  • 2.
    Andersson, Helene
    et al.
    Sophiahemmet Högskola.
    Andreassen, Sissel
    Sophiahemmet Högskola.
    Lindholm, Christina
    Sophiahemmet Högskola.
    Fossum, Bjöörn
    Sophiahemmet Högskola.
    Emotional reactions when caring for MRSA-positive patients: ignorance and fear versus knowledge and securityArtikkel i tidsskrift (Fagfellevurdert)
  • 3.
    Andersson, Helene
    et al.
    Sophiahemmet Högskola.
    Lindholm, Christina
    Sophiahemmet Högskola.
    Iversen, Aina
    Giske, Christian G
    Örtqvist, Åke
    Kalin, Mats
    Fossum, Bjöörn
    Sophiahemmet Högskola.
    Prevalence of antibiotic-resistant bacteria in residents of nursing homes in a Swedish municipality: healthcare staff knowledge of and adherence to principles of basic infection prevention2012Inngår i: Scandinavian journal of infectious diseases, ISSN 1651-1980, Vol. 44, nr 9, s. 641-649Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Abstract Background: The aims of this study were to investigate the prevalence of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE) and extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in residents living in Swedish nursing homes, and if carriage of resistant bacteria was related to antibiotic treatment, other risk factors, and/or staff's adherence to guidelines for infection control. Methods: Five hundred and sixty residents from 9 nursing homes on a total of 67 wards participated in the study and had microbiological cultures taken. Faecal samples were obtained from 495 residents (88.3%). ESBL-positive residents were followed for 2 y with repeated sampling. Two hundred and ninety-six staff members were interviewed and observed regarding familiarity with and adherence to infection control guidelines. Results: No resident was positive for MRSA or VRE. Fifteen of the residents were found to be ESBL-positive. Residents living on wards where ESBL-positive residents were identified had been treated more frequently with antibiotics (42%), compared to those on wards where no residents with ESBL were found (28%; p = 0.02). ESBL-positive Escherichia coli isolates from residents living in adjacent rooms were found to be closely genetically related when analysed by pulsed-field gel electrophoresis, indicating transmission between residents. Staff adherence to infection control guidelines sometimes revealed shortcomings, but no significant differences regarding compliance to the guidelines could be found. Conclusion: Carriage of resistant bacteria was uncommon and only ESBL-producing Enterobacteriaceae were identified in Swedish nursing homes. Usage of antibiotics was higher on wards where ESBL-positive residents were detected and there was an indication of transmission of ESBL between residents.

  • 4. Butler, Eile
    et al.
    Oien, Rut F
    Lindholm, Christina
    Sophiahemmet Högskola.
    Olofsson, Tobias C
    Nilson, Bo
    Vásquez, Alejandra
    A pilot study investigating lactic acid bacterial symbionts from the honeybee in inhibiting human chronic wound pathogens2016Inngår i: International Wound Journal, ISSN 1742-4801, E-ISSN 1742-481X, Vol. 13, nr 5, s. 729-37Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Treatment and management of chronic wounds is a large burden on the health sector and causes substantial suffering for the patients. We believe that 13 lactic acid bacteria (LAB) symbionts isolated from the honey crop of the honeybee are important players in the antimicrobial action of honey, by producing antimicrobial substances and can be used in combination with heather honey as an effective treatment in wound management. A total of 22 patients with chronic ulcers were included; culture-dependent and molecular-based (MALDI-MS and 16S rRNA gene sequencing) techniques were used to identify bacteria from chronic wounds. These clinical isolates were used for in vitro antimicrobial testing with standardised viable LAB and sterilised heather honey mixture. Twenty of the patients' wounds were polymicrobial and 42 different species were isolated. Patient isolates that were tested in vitro were inhibited by the LAB and honey combination with inhibitory zones comparable with different antibiotics. LAB and heather honey in combination presents a new topical option in chronic wound management because of the healing properties of honey, antimicrobial metabolite production from the LAB and their bactericidal effect on common chronic wound pathogens. This new treatment may be a stepping stone towards an alternative solution to antibiotics.

  • 5. Ek, Anna-Christina
    et al.
    Lindholm, Christina
    Sophiahemmet Högskola.
    Trycksår. Reviderad 20132013Inngår i: Vårdhandboken / [ed] Annika Ahrnstedt & Monica Andersson, Stockholm: Stockholms läns landsting , 2013Kapittel i bok, del av antologi (Annet vitenskapelig)
  • 6.
    Eulau, Louise
    et al.
    Sophiahemmet Högskola.
    Paulander, Ann-Sophie
    Lindholm, Christina
    Sophiahemmet Högskola.
    PC-Music: a cross disciplinary model combining nursing and music therapy as pain management2016Konferansepaper (Annet vitenskapelig)
    Abstract [en]

    While nursing and music therapy have been two important disciplines in analysis of pain management, there has been little research exploring these areas from a cross disciplinary perspective. This paper highlights the importance of acknowledging and beginning to understand the role of scientific and practical cooperation between music therapists and health care professionals.

    In particular, our aim has been to initiate a dialogue about how subject-specific knowledge from both music therapy and nursing – in terms of person-centered care – can strengthen the usage of music as pain management for short-term management of acute pain during painful treatments such as dressing change procedure in wound care. On this basis, a pilot study was conducted regarding wound care. The study has been approved by the ethics committee in Stockholm. The paper is based on the result from this study where the aim was to find a model for pain management as a complementary treatment based on knowledge from nursing and music therapy.

    Philosophical starting points were the “life-world” perspective of Merleau-Ponty as well as Ricoeur’s ethical thoughts. The result has a potential reach beyond wound care that can be used in several treatments that entails acute pain.

  • 7. Gardulf, Ann
    et al.
    Florin, Jan
    Carlsson, Marianne
    Leksell, Janeth
    Lepp, Margret
    Lindholm, Christina
    Sophiahemmet Högskola.
    Nordström, Gun
    Theander, Kersti
    Wilde-Larsson, Bodil
    Nilsson, Jan
    Sophiahemmet Högskola.
    The Nurse Professional Competence (NPC) Scale: A tool that can be used in national and international assessments of nursing education programmes2019Inngår i: Nordic journal of nursing research, ISSN 2057-1585, E-ISSN 2057-1593, Vol. 39, nr 3, s. 137-142Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The quality of basic nursing bachelor programmes nationally and internationally must regularly be assessed to ensure that they fulfil requirements and are appropriate in relation to developments and changes in societies and healthcare systems. There is a need for instruments in helping to assess this. The aim of this study was to investigate whether the Nurse Professional Competence (NPC) Scale could serve as a tool to measure and detect possible differences between universities/university colleges regarding nursing students' self-reported competence. Totally, 543 nursing students who had just completed their academic three-year nursing bachelor programmes at 10 universities/university colleges in Sweden participated in the study (response rate 71%). The students answered the NPC Scale with its 88 items constituting eight competence areas (CAs) and two overarching themes. The results from using the NPC Scale by the students were then compared between the 10 universities/university colleges. Significant mean score differences were found between the universities/university colleges on all CAs and on both themes. The highest mean score differences were found for the CAs 'Medical and technical care' and 'Documentation and information technology'. The lowest mean score differences were found for the CAs 'Value-based nursing care' and 'Leadership in and development of nursing'. It is concluded that the NPC Scale can serve as a useful tool in national and international assessments of nursing bachelor programmes.

  • 8. Gardulf, Ann
    et al.
    Nilsson, Jan
    Florin, Jan
    Leksell, Janeth
    Lepp, Margret
    Lindholm, Christina
    Sophiahemmet Högskola.
    Nordström, Gun
    Theander, Kersti
    Wilde-Larsson, Bodil
    Carlsson, Marianne
    Johansson, Eva
    The Nurse Professional Competence (NPC) Scale: Self-reported competence among nursing students on the point of graduation2016Inngår i: Nurse Education Today, ISSN 0260-6917, E-ISSN 1532-2793, Vol. 36, s. 165-171Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    BACKGROUND: International organisations, e.g. WHO, stress the importance of competent registered nurses (RN) for the safety and quality of healthcare systems. Low competence among RNs has been shown to increase the morbidity and mortality of inpatients.

    OBJECTIVES: To investigate self-reported competence among nursing students on the point of graduation (NSPGs), using the Nurse Professional Competence (NPC) Scale, and to relate the findings to background factors.

    METHODS AND PARTICIPANTS: The NPC Scale consists of 88 items within eight competence areas (CAs) and two overarching themes. Questions about socio-economic background and perceived overall quality of the degree programme were added. In total, 1086 NSPGs (mean age, 28.1 [20-56]years, 87.3% women) from 11 universities/university colleges participated.

    RESULTS: NSPGs reported significantly higher scores for Theme I "Patient-Related Nursing" than for Theme II "Organisation and Development of Nursing Care". Younger NSPGs (20-27years) reported significantly higher scores for the CAs "Medical and Technical Care" and "Documentation and Information Technology". Female NSPGs scored significantly higher for "Value-Based Nursing". Those who had taken the nursing care programme at upper secondary school before the Bachelor of Science in Nursing (BSN) programme scored significantly higher on "Nursing Care", "Medical and Technical Care", "Teaching/Learning and Support", "Legislation in Nursing and Safety Planning" and on Theme I. Working extra paid hours in healthcare alongside the BSN programme contributed to significantly higher self-reported scores for four CAs and both themes. Clinical courses within the BSN programme contributed to perceived competence to a significantly higher degree than theoretical courses (93.2% vs 87.5% of NSPGs).

    SUMMARY AND CONCLUSION: Mean scores reported by NSPGs were highest for the four CAs connected with patient-related nursing and lowest for CAs relating to organisation and development of nursing care. We conclude that the NPC Scale can be used to identify and measure aspects of self-reported competence among NSPGs.

  • 9.
    Lindholm, Christina
    Sophiahemmet Högskola.
    Naturens läkekonster - sårläkning i ett naturhistoriskt perspektiv2013Inngår i: Smittskydd Stockholm, Vol. 24, nr 3, s. 11-Artikkel i tidsskrift (Annet (populærvitenskap, debatt, mm))
  • 10.
    Lindholm, Christina
    Sophiahemmet Högskola.
    Omvårdnad vid sår2014Inngår i: Omvårdnadens grunder: hälsa och ohälsa / [ed] Anna-Karin Edberg & Helle Wijk, Lund: Studentlitteratur AB, 2014, 2, s. 495-525Kapittel i bok, del av antologi (Annet vitenskapelig)
  • 11.
    Lindholm, Christina
    Sophiahemmet Högskola.
    Sår2012 (oppl. 3)Bok (Annet vitenskapelig)
  • 12.
    Lindholm, Christina
    Sophiahemmet Högskola.
    Trycksår i geriatrisk vård: en patient, flera vårdgivare2013Inngår i: Svensk geriatrik : äldrevård och äldremedicin i öppen och sluten vård, ISSN 2001-2047, Vol. 2, nr 4, s. 9-12Artikkel i tidsskrift (Annet (populærvitenskap, debatt, mm))
  • 13.
    Lindholm, Christina
    Sophiahemmet Högskola.
    Trycksår i livets slutskede2014Inngår i: SårMagasinet, ISSN 2001-9920, Vol. 1, nr 1, s. 46--49Artikkel i tidsskrift (Annet vitenskapelig)
  • 14.
    Lindholm, Christina
    et al.
    Sophiahemmet Högskola.
    Cornelius, Maria
    Leo Swenne, Christine
    Sår vid kirurgi och trauma2016Inngår i: Omvårdnad & kirurgi / [ed] Christine Kumlien & Jenny Rystedt, Lund: Studentlitteratur AB, 2016, 1, s. 133-146Kapittel i bok, del av antologi (Annet vitenskapelig)
  • 15.
    Lindholm, Christina
    et al.
    Sophiahemmet Högskola.
    Grauers, Margareta
    Sårbehandling 2013/2014: katalog över sårprodukter2013Collection/Antologi (Annet (populærvitenskap, debatt, mm))
  • 16.
    Lindholm, Christina
    et al.
    Sophiahemmet Högskola.
    Grauers, Margareta
    Sårbehandling 2017/2018: katalog över sårprodukter2017Collection/Antologi (Annet (populærvitenskap, debatt, mm))
  • 17.
    Lindholm, Christina
    et al.
    Sophiahemmet Högskola.
    Searle, Richard
    Wound management for the 21st century: combining effectiveness and efficiency2016Inngår i: International Wound Journal, ISSN 1742-4801, E-ISSN 1742-481X, Vol. 13, nr Suppl 2, s. 5-15Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Treatment of wounds of different aetiologies constitutes a major part of the total health care budget. It is estimated that 1·5-2 million people in Europe suffer from acute or chronic wounds. These wounds are managed both in hospitals and in community care. The patients suffering from these wounds report physical, mental and social consequences of their wounds and the care of them. It is often believed that the use of wound dressings per se is the major cost driver in wound management, whereas in fact, nursing time and hospital costs are together responsible for around 80-85% of the total cost. Healing time, frequency of dressing change and complications are three important cost drivers. However, with the use of modern, advanced technology for more rapid wound healing, all these cost drivers can be substantially reduced. A basic understanding of the terminology and principles of Health Economics in relation to wound management might therefore be of interest.

  • 18.
    Lindholm, Christina
    et al.
    Sophiahemmet Högskola.
    Styche, Tim J
    Horton, Helen E
    Diagnosis and treatment impacts on wound care efficiency drivers: Real-world analysis2021Inngår i: Journal of Wound Care, ISSN 0969-0700, E-ISSN 2052-2916, Vol. 30, nr 7, s. 534-542Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objective: The prevalence and economic burden of wounds are growing. Any wound has the potential to become hard-to-heal and require frequent care. Clinicians need to find ways to absorb demand on services without compromising outcomes. Drivers of wound care efficiency-time-to-heal, frequency of dressing change and the incidence of complications-can be evaluated to shape future wound management. A survey of wound care was conducted by clinicians from five centres in Sweden over a one-week period, during which clinicians documented every wound once. At the time of surveying, 49% of wounds were considered to be improving, infection incidence was 11.7% and dressings were changed a mean of 2.2 times per week, with highly exuding wounds changed 6.9 times per week. The data highlighted the importance of diagnosing patient and wound characteristics in selecting treatments and organising care. Recognised gaps in diagnoses potentially identify opportunities to influence healing, complication incidence and intensity of nursing, thus reducing demand on resources. In conclusion, this survey highlights opportunities to reduce the burdens these drivers present. Through improved diagnosis and alignment to recognised care pathways, there is potential to improve patient outcomes and alleviate the strains placed upon wound care providers.

  • 19.
    Lindholm, Christina
    et al.
    Sophiahemmet Högskola.
    Tammelin, Ann
    Häggström, Christer
    Sårbehandling. Reviderad 20132013Inngår i: Vårdhandboken / [ed] Annika Ahrnstedt & Monica Andersson, Stockholm: Stockholms läns landsting , 2013Kapittel i bok, del av antologi (Annet vitenskapelig)
  • 20. Nilsson, Jan
    et al.
    Johansson, Eva
    Carlsson, Marianne
    Florin, Jan
    Leksell, Janeth
    Lepp, Margret
    Lindholm, Christina
    Sophiahemmet Högskola.
    Nordström, Gun
    Theander, Kersti
    Wilde-Larsson, Bodil
    Gardulf, Ann
    Disaster nursing: Self-reported competence of nursing students and registered nurses, with focus on their readiness to manage violence, serious events and disasters2015Inngår i: Nurse Education in Practice, ISSN 1471-5953, E-ISSN 1873-5223, Vol. 17, s. 102-108Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The World Health Organization and the International Council of Nurses recognises the importance of nurses' involvement in disaster preparedness and response. The aim of this study was to describe and compare self-reported disaster nursing competence (DNC) among nursing students (NSs) and among registered nurses (RNs) with professional experience. Further to investigate possible associations between self-reported DNC and background factors. A cross-sectional study was conducted of 569 NSs and 227 RNs. All respondents completed the 88-item Nurse Professional Competence Scale, including three items assessing DNC. Significant differences were found among the NSs depending on which University/University College they had attended. RNs reported significantly higher overall DNC and better ability to handle situations involving violence, and to apply principles of disaster medicine during serious events. RNs working in emergency care reported significantly better DNC ability, compared with RNs working in other areas of healthcare. Multiple linear regression analysis showed that working night shift and working in emergency care were positively associated with high self-reported overall DNC. The results indicate that workplace experience of serious events increase the readiness of registered nurses to handle violence, to act in accordance with safety regulations, and to apply principles of disaster medicine during serious events.

  • 21. Nilsson, Jan
    et al.
    Johansson, Eva
    Egmar, Ann-Charlotte
    Florin, Jan
    Leksell, Janeth
    Lepp, Margret
    Lindholm, Christina
    Sophiahemmet Högskola.
    Nordström, Gun
    Theander, Kersti
    Wilde-Larsson, Bodil
    Carlsson, Marianne
    Gardulf, Ann
    Development and validation of a new tool measuring nurses self-reported professional competence --the nurse professional competence (NPC) Scale2014Inngår i: Nurse Education Today, ISSN 0260-6917, E-ISSN 1532-2793, Vol. 34, nr 4, s. 574-580Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    OBJECTIVES: To develop and validate a new tool intended for measuring self-reported professional competence among both nurse students prior to graduation and among practicing nurses. The new tool is based on formal competence requirements from the Swedish Board of Health and Welfare, which in turn are based on WHO guidelines.

    DESIGN: A methodological study including construction of a new scale and evaluation of its psychometric properties.

    PARTICIPANTS AND SETTINGS: 1086 newly graduated nurse students from 11 universities/university colleges.

    RESULTS: The analyses resulted in a scale named the NPC (Nurse Professional Competence) Scale, consisting of 88 items and covering eight factors: "Nursing care", "Value-based nursing care", "Medical/technical care", "Teaching/learning and support", "Documentation and information technology", "Legislation in nursing and safety planning", "Leadership in and development of nursing care" and "Education and supervision of staff/students". All factors achieved Cronbach's alpha values greater than 0.70. A second-order exploratory analysis resulted in two main themes: "Patient-related nursing" and "Nursing care organisation and development". In addition, evidence of known-group validity for the NPC Scale was obtained.

    CONCLUSIONS: The NPC Scale, which is based on national and international professional competence requirements for nurses, was comprehensively tested and showed satisfactory psychometrical properties. It can e.g. be used to evaluate the outcomes of nursing education programmes, to assess nurses' professional competences in relation to the needs in healthcare organisations, and to tailor introduction programmes for newly employed nurses.

  • 22. Olofsson, Tobias C
    et al.
    Butler, Eile
    Markowicz, Pawel
    Lindholm, Christina
    Sophiahemmet Högskola.
    Larsson, Lennart
    Vásquez, Alejandra
    Lactic acid bacterial symbionts in honeybees - an unknown key to honey's antimicrobial and therapeutic activities2016Inngår i: International Wound Journal, ISSN 1742-4801, E-ISSN 1742-481X, Vol. 13, nr 5, s. 668-79Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Could honeybees' most valuable contribution to mankind besides pollination services be alternative tools against infections? Today, due to the emerging antibiotic-resistant pathogens, we are facing a new era of searching for alternative tools against infections. Natural products such as honey have been applied against human's infections for millennia without sufficient scientific evidence. A unique lactic acid bacterial (LAB) microbiota was discovered by us, which is in symbiosis with honeybees and present in large amounts in fresh honey across the world. This work investigates if the LAB symbionts are the source to the unknown factors contributing to honey's properties. Hence, we tested the LAB against severe wound pathogens such as methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa and vancomycin-resistant Enterococcus (VRE) among others. We demonstrate a strong antimicrobial activity from each symbiont and a synergistic effect, which counteracted all the tested pathogens. The mechanisms of action are partly shown by elucidating the production of active compounds such as proteins, fatty acids, anaesthetics, organic acids, volatiles and hydrogen peroxide. We show that the symbionts produce a myriad of active compounds that remain in variable amounts in mature honey. Further studies are now required to investigate if these symbionts have a potential in clinical applications as alternative tools against topical human and animal infections.

  • 23. Olofsson, Tobias C
    et al.
    Butler, Éile
    Lindholm, Christina
    Sophiahemmet Högskola.
    Nilson, Bo
    Michanek, Per
    Vásquez, Alejandra
    Fighting Off Wound Pathogens in Horses with Honeybee Lactic Acid Bacteria.2016Inngår i: Current Microbiology, ISSN 0343-8651, E-ISSN 1432-0991, Vol. 73, nr 4, s. 463-73Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    In the global perspective of antibiotic resistance, it is urgent to find potent topical antibiotics for the use in human and animal infection. Healing of equine wounds, particularly in the limbs, is difficult due to hydrostatic factors and exposure to environmental contaminants, which can lead to heavy bio-burden/biofilm formation and sometimes to infection. Therefore, antibiotics are often prescribed. Recent studies have shown that honeybee-specific lactic acid bacteria (LAB), involved in honey production, and inhibit human wound pathogens. The aim of this pilot study was to investigate the effects on the healing of hard-to-heal equine wounds after treatment with these LAB symbionts viable in a heather honey formulation. For this, we included ten horses with wound duration of >1 year, investigated the wound microbiota, and treated wounds with the novel honeybee LAB formulation. We identified the microbiota using MALDI-TOF mass spectrometry and DNA sequencing. In addition, the antimicrobial properties of the honeybee LAB formulation were tested against all wound isolates in vitro. Our results indicate a diverse wound microbiota including fifty-three bacterial species that showed 90 % colonization by at least one species of Staphylococcus. Treatment with the formulation promoted wound healing in all cases already after the first application and the wounds were either completely healed (n = 3) in less than 20 days or healing was in progress. Furthermore, the honeybee LAB formulation inhibited all pathogens when tested in vitro. Consequently, this new treatment option presents as a powerful candidate for the topical treatment of hard-to-heal wounds in horses.

  • 24. Pokorná, A
    et al.
    Öien, R. F
    Forssell, H
    Lindholm, Christina
    Sophiahemmet Högskola.
    International Cooperation in Pressure Ulcers Prevalence, Prevention and Treatment is Chal lenged by the Lack of National Registries.2016Inngår i: Česká a Slovenská neurologie a neurochirurgie, ISSN 1210-7859, Vol. 79, nr Suppl. 1, s. 20-24Artikkel i tidsskrift (Fagfellevurdert)
  • 25. Skavberg Roaldsen, Kirsti
    et al.
    Lindholm, Christina
    Sophiahemmet Högskola.
    Fysisk aktivitet och träning vid venös och arteriell insufficiens och bensår2012Inngår i: Äldres hälsa: ett sjukgymnastiskt perspektiv / [ed] Elisabeth Rydwik, Lund: Studentlitteratur, 2012, 1, s. 259-270Kapittel i bok, del av antologi (Annet vitenskapelig)
  • 26. Stenius, Madeleine
    Trycksår: med livet som insats2016Bok (Annet (populærvitenskap, debatt, mm))
  • 27.
    Sterner, Eila
    et al.
    Sophiahemmet Högskola.
    Fossum, Bjöörn
    Sophiahemmet Högskola.
    Berg, Elisabeth
    Lindholm, Christina
    Sophiahemmet Högskola.
    Stark, André
    Objective evaluation by reflectance spectrophotometry can be of clinical value for the verification of blanching/nonblanching erythema in the sacral area2014Inngår i: International Wound Journal, ISSN 1742-4801, E-ISSN 1742-481X, Vol. 11, nr 4, s. 416-423Artikkel i tidsskrift (Fagfellevurdert)
  • 28.
    Sterner, Eila
    et al.
    Sophiahemmet Högskola.
    Unbeck, M
    Lindholm, Christina
    Sophiahemmet Högskola.
    Stark, A
    Gordon, M
    Fossum, Bjöörn
    Sophiahemmet Högskola.
    Poor documentation of risk factors and prevention strategies for pressure ulcers in orthopedic inpatientsManuskript (preprint) (Annet vitenskapelig)
  • 29. Theander, Kersti
    et al.
    Wilde-Larsson, Bodil
    Carlsson, Marianne
    Florin, Jan
    Gardulf, Ann
    Johansson, Eva
    Lindholm, Christina
    Sophiahemmet Högskola.
    Nordström, Gun
    Nilsson, Jan
    Adjusting to future demands in healthcare: Curriculum changes and nursing students' self-reported professional competence2015Inngår i: Nurse Education Today, ISSN 0260-6917, E-ISSN 1532-2793, Vol. 37, s. 178-183Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    BACKGROUND: Nursing competence is of significant importance for patient care. Newly graduated nursing students rate their competence as high. However, the impact of different designs of nursing curricula on nursing students' self-reported nursing competence areas is seldom reported.

    OBJECTIVES: To compare newly graduated nursing students' self-reported professional competence before and after the implementation of a new nursing curriculum. The study had a descriptive comparative design. Nursing students, who graduated in 2011, having studied according to an older curriculum, were compared with those who graduated in 2014, after a new nursing curriculum with more focus on person-centered nursing had been implemented.

    SETTING: A higher education nursing program at a Swedish university.

    PARTICIPANTS: In total, 119 (2011 n=69, 2014 n=50) nursing students responded.

    METHODS: Nursing students' self-reported professional competencies were assessed with the Nurse Professional Competence (NPC) scale.

    RESULTS: There were no significant differences between the two groups of nursing students, who graduated in 2011 and 2014, respectively, with regard to age, sex, education, or work experience. Both groups rated their competencies as very high. Competence in value-based nursing was perceived to be significantly higher after the change in curriculum. The lowest competence, both in 2011 and 2014, was reported in education and supervision of staff and students.

    CONCLUSIONS: Our findings indicate that newly graduated nursing students - both those following the old curriculum and the first batch of students following the new one - perceive that their professional competence is high. Competence in value-based nursing, measured with the NPC scale, was reported higher after the implementation of a new curriculum, reflecting curriculum changes with more focus on person-centered nursing.

  • 30. Zubair, Muhammad
    et al.
    Nybom, Hilde
    Lindholm, Christina
    Sophiahemmet Högskola.
    Brandner, Johanna M
    Rumpunen, Kimmo
    Promotion of wound healing by Plantago major L. leaf extracts: Ex-vivo experiments confirm experiences from traditional medicine2016Inngår i: Natural Product Research, ISSN 1478-6419, E-ISSN 1478-6427, Vol. 30, nr 5, s. 622-624Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The wound-healing properties of Plantago major L. (plantain) were evaluated using an ex-vivo porcine wound-healing model. Ethanol- and water-based extracts were prepared from greenhouse-grown and freeze-dried leaves of P. major. Both types of extracts stimulated wound healing in porcine skin, but the ethanol-based extracts had a somewhat stronger effect. A concentration of 1.0 mg/mL (on dry weight basis) produced the best results for both types of extracts.

  • 31.
    Lindholm, Christina
    Sophiahemmet Högskola.
    Svårläkta sår hos äldre - prevention och behandling: En systematisk litteraturöversikt2014Rapport (Fagfellevurdert)
    Abstract [sv]

    Svårläkta sår hos äldre och sköra äldre är ett stort problem framför allt för den drabbade patienten med smärta och nedsatt livskvalitet. För hälso- och sjukvården medför svårläkta sår betydande resursbehov och kostnader för behandling.

    Svårläkta sår innefattar bensår, fotsår hos personer med eller utan diabetes samt trycksår. Dessa sår är vanliga i äldrevården och risken ökar med stigande ålder. I dag utgör åldersgruppen 65 år eller äldre, en femtedel av Sveriges befolkning eller cirka 1,8 miljoner och är snabbt växande. År 2030 beräknas var fjärde person vara 65 år eller äldre.

    Denna rapport grundar sig på vetenskapliga artiklar gällande prevention av bensår och fotsår samt behandling av trycksår, bensår och fotsår hos äldre. Förebyggande av trycksår har inte tagits med då det pågår ett internationellt arbete med att uppdatera en systematisk översikt på området.

    SBU:s slutsatser

    • Det vetenskapliga underlaget för behandling av svårläkta sår hos äldre är mycket begränsat. För majoriteten av åtgärderna behövs det mer forskning av god vetenskaplig kvalitet. Gruppen äldre/sköra äldre har ofta flera sjukdomar och läkemedel samtidigt, något som kan inverka på sårläkningen.
    • Det saknas data om hur svensk praxis ser ut i dag och i vilken utsträckning som olika åtgärder för att förebygga och behandla svårläkta sår används. Kvalitetsregister med representativa data för vissa patientgrupper finns, men nationellt heltäckande data saknas i nuläget. Det finns ett begränsat vetenskapligt underlag för följande effekter:- Operation av åderbråck kan minska återfall av venösa bensår hos äldre.- Förband som innehåller kalciumalginat kan leda till kortare läkningstid av trycksår hos äldre medan läkningseffekten av övriga förband inte kan uppskattas då studier saknas.
    • Det finns stora kunskapsluckor när det gäller vårdorganisationens betydelse för patienter med svårläkta sår. Det gäller t ex betydelsen av specialistmottagningar, utbildning, kommunikation, samordning och kontinuitet.
    • Åderbråckskirurgi som behandling av venösa bensår är sannolikt kostnadseffektivt. Kostnadseffektiviteten av övriga insatser är svår att bedöma. 
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