shh.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Quality of life in men with metastatic prostate cancer in their final years before death: a retrospective analysis of prospective data
Sophiahemmet University.ORCID iD: 0000-0003-2074-5985
Sophiahemmet University.ORCID iD: 0000-0002-8780-5922
Sophiahemmet University.ORCID iD: 0000-0002-3457-4737
Show others and affiliations
2018 (English)In: BMC Palliative Care, ISSN 1472-684X, E-ISSN 1472-684X, Vol. 17, no 1, article id 126Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Quality of Life (QoL) is the most important outcome for patients in palliative care along with symptom alleviation. Metastatic prostate cancer (mPC) is a life-threatening illness, and hence, a palliative care approach may be beneficial to this group. Over time, new life-prolonging treatments have been developed for men with mPC, but the possibility to prolong life should also be balanced against the men's QoL, particularly because there are side effects involved with these treatments. The aim of this study was to evaluate QoL, functioning and symptoms in men with mPC during their final years before death.

METHODS: This is a retrospective analysis of data from a long-term prospective study of men (n = 3885) with prostate cancer from two regions in Sweden. Validated questionnaires asking about participants' QoL, functioning and symptoms were used to collect data. From the overall study, 190 men with mPC were identified. They were stratified into three groups, depending on the amount of time that had passed between the last questionnaire and their death; < 6 months, 6-18 months and > 18 months before death.

RESULTS: Men with mPC generally rated their QoL poorly compared to established clinically significant threshold values. The group of men that were < 6 months before death rated their QoL, functioning and several symptoms significantly worse than the two other groups. Men that died after the year 2006 reported lower QoL and functioning and more pain and fatigue than those who died before 2006.

CONCLUSION: The results in this study indicate that men with mPC have unmet needs with regards to QoL and symptoms. A palliative care approach, alongside possible life-prolonging treatments, that focuses on QoL and symptom relief, may serve as an important frame to give the best support to these men in their final years of life.

Place, publisher, year, edition, pages
2018. Vol. 17, no 1, article id 126
Keywords [en]
Life-prolonging treatment, Metastatic disease, Palliative care, Prostate cancer, Quality of life
National Category
Cancer and Oncology
Identifiers
URN: urn:nbn:se:shh:diva-3179DOI: 10.1186/s12904-018-0381-6PubMedID: 30509249OAI: oai:DiVA.org:shh-3179DiVA, id: diva2:1268722
Available from: 2018-12-06 Created: 2018-12-06 Last updated: 2019-02-20Bibliographically approved

Open Access in DiVA

fulltext(763 kB)20 downloads
File information
File name FULLTEXT01.pdfFile size 763 kBChecksum SHA-512
437f8dd01360eabce269f44b2552d2c2f2343c0d5f16adc7c8c3c2618b0a77e740e18171b9b11765d630efb0665561a8087100110367d62f8fc95a2449ac5737
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Holm, MajaDoveson, SandraWennman-Larsen, Agneta
By organisation
Sophiahemmet University
In the same journal
BMC Palliative Care
Cancer and Oncology

Search outside of DiVA

GoogleGoogle Scholar
Total: 20 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 22 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
v. 2.35.7
|