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Important factors associated with sick leave after allogeneic haematopoietic stem cell transplantation: A 1-year prospective study
Sophiahemmet University.ORCID iD: 0000-0002-3457-4737
Sophiahemmet University.ORCID iD: 0000-0002-6331-8599
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2021 (English)In: Journal of cancer survivorship, ISSN 1932-2259, E-ISSN 1932-2267, Vol. 15, no 6, p. 933-941Article in journal (Refereed) Published
Abstract [en]

PURPOSE: This study examines sick leave (SL) and factors associated with full-time SL 1 year after allogeneic haematopoietic stem cell transplantation (allo-HSCT) in patients of working age from 2009 to 2016 (n = 122).

METHODS: Questionnaire data were collected on admission to the allo-HSCT unit, at 7 months and 1 year after allo-HSCT. Associations between factors and SL were analysed using logistic regression analyses.

RESULTS: One year after allo-HSCT, 76% of participants were on SL, with 36% on full-time SL. In univariable analyses, chronic graft-versus-host-disease (cGvHD) (OR 3.07; 95% CI 1.34-7.07; p = 0.01), having symptoms of depression at 7 months (OR 4.81; 95% CI 1.69-13.69; p = 0.00) and low levels of vocational satisfaction at 7 months after treatment (OR 3.27; 95% CI 1.27-8.41; p = 0.01) were associated with full-time SL 1 year after allo-HSCT. cGvHD (OR 3.43; 95% CI 1.35-8.73; p = 0.01) and having symptoms of depression at 7 months after allo-HSCT (OR 3.37; 95% CI 1.2-11.58; p = 0.02) remained significant in multivariable analysis.

CONCLUSION: The majority of allo-HSCT survivors were on SL 1 year after treatment, and cGvHD, low vocational satisfaction and depressive symptoms were associated with full-time SL 1 year after allo-HSCT.

IMPLICATIONS FOR CANCER SURVIVORS: Healthcare professionals need to be observant of and manage the consequences of cGvHD and patients' symptoms of depression in order to support them appropriately in their return-to-work process.

Place, publisher, year, edition, pages
2021. Vol. 15, no 6, p. 933-941
Keywords [en]
Allogeneic haematopoietic stem cell transplantation, Return to work, Sick leave, Sickness absence
National Category
Cancer and Oncology
Identifiers
URN: urn:nbn:se:shh:diva-3965DOI: 10.1007/s11764-020-00986-5PubMedID: 33417181OAI: oai:DiVA.org:shh-3965DiVA, id: diva2:1530380
Available from: 2021-02-22 Created: 2021-02-22 Last updated: 2022-01-07Bibliographically approved

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Wennman-Larsen, AgnetaBergkvist, Karin

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